SC Center for Grassroots & Nonprofit Leadership

The Center seeks to actively build capacity and enhance resources of community and faith-based grassroots groups, nonprofit organizations, and individuals that are challenged to provide leadership and improve community life.

Urban League of the Upstate

The Urban League of the Upstate is a non-profit organization committed to the principle of equal opportunity for all citizens in housing, education, employment, and economic development, without regard to race or socioeconomic status.

Donate Blood

The nation’s blood banks, represented by the American Red Cross, American Association of Blood Banks, and America’s Blood Centers, are asking for immediate blood donations to boost already low blood supplies. Blood is traditionally in short supply due to the holidays, travel schedules, inclement weather, and illness.  Individuals are asked to support their local blood centers by making and keeping an appointment to donate immediately.

New Day, Inc. of Spartanburg

Also known as New Day Clubhouse, New Day was founded in 1987 as a private, nonprofit organization through the efforts of the Mental Health Association of the Piedmont. New Day was established to fill the community’s need for a psychiatric rehabilitation center serving adults, 18 years and older, with diagnoses of serious and persistent mental illness.

Mental Health America

Mental Health America (MHA) – founded in 1909 – is the nation’s leading community-based nonprofit dedicated to addressing the needs of those living with mental illness and promoting the overall mental health of all Americans. Find help, support groups, informational articles, and help get connected to a health care provider on our website. If you are in crisis and need immediate help please call 1-800-273-TALK (8255).

Bethlehem Center

The Bethlehem Center, established in 1930, is currently a multi-service Agency providing an array of programs to residents in Spartanburg County. The Center’s day care facility has the capacity to serve 48 children between the ages of two and five. After school tutorial services, fine arts, sports and recreational activities, scouting, seasonal camping, primary prevention, and leadership programs for community youth are also available. Programming for adults includes Bible studies and fellowship, nutrition programs, life skills sessions, as well as sewing and craft classes.

A computer lab is maintained for all program participants and community residents.

Spartanburg Humane Society

The Humane Society is a non-profit, charitable organization dedicated to the promotion of animal welfare throughout Spartanburg and surrounding areas. The Societyworks to make our community a safer place for people to live, to prevent cruelty to animals, and to educate the public in proper animal care, especially the neutering of pets.

Mary Black Foundation

Our mission is to improve the health and wellness of the people and communities of Spartanburg County. We define “health and wellness” broadly — as complete physical, mental, and social well-being — and devote the majority of our resources to efforts that address the underlying causes of poor health outcomes in Spartanburg County.

Alston Wilkes Society

Alston Wilkes Society provides support services to adult and juvenile offenders, former offenders and the homeless. Services include case management, employment assistance and referrals to other resources as needed. For more information, or the office closest to you, call our main office.

Miracle Hill Ministries

Miracle Hill Rescue Mission – Spartanburg, formerly Downtown Rescue Mission, came under the Miracle Hill Ministries umbrella in July 2002. The shelter houses men, women, and families all in seperate quarters.

SC Ovarian Cancer Foundation

This is an organization brought together by ovarian cancer patients, healthcare providers, and other concerned individuals for the dissemination of information about ovarian cancer. It has been designed for the patients, for support, for education of the public and healthcare providers, and for the furthering of research in ovarian cancer in the state of South Carolina. The Foundation has affiliations with major gynecologic oncology centers in this state.

The South Carolina Centers for Equal Justice

The South Carolina Centers for Equal Justice, and its predecessors, through its offices in Anderson, Greenville and Spartanburg have been providing free civil legal assistance to the low income community in the Upstate for nearly 40 years. Call toll-free, 1-888-346-5592.
303 East River Street, Anderson
701 South Main Street, Greenville
148 East Main Street, Spartanburg

Hope and Light Foundation

Hope and Light Foundation is dedicated to funding research to eliminate SMA, a deadly genetic disease and the leading genetic killer of babies and toddlers under the age of two. Hope and Light hopes educate families and communities about the existence of this disease.

Habitat for Humanity of Spartanburg, Inc.

Habitat for Humanity of Spartanburg, Inc. is a Christian housing ministry building simple, affordable homes for deserving, needy families. Habitat homeowners buy their homes at cost with a 30 year term mortgage and must perform 250 hours of “sweat equity” building their own home or other Habitat homes. We provide a “hand up” instead of a “hand out”.

Children’s Shelter

Children’s Shelter is a temporary shelter where placement cannot exceed 30 days.

Spartanburg County Volunteer Guardian ad Litem Program

Children who enter the foster care system are in need of caring adults to speak up for them in Family Court. The Guardian ad Litem is a strong child advocate for children. If you are over 21 and can give 4-5 hours a month to visit a child, you can change a child’s life. You do not need a college degree, or a legal or social work background. The very best child advocates are people who care about children. Visit our website, email [email protected], or call 800-277-0113 for additional information.

Junior Achievement of Spartanburg, Inc.

Junior Achievement of Spartanburg, Inc. has taught over 45,000 area students about business and the world of work. Last year alone, the organization helped instill an entrepreneurial spirit and an appreciation of the American free enterprise system in 4,000 young people in 214 JA classes.

Baby & Me – Tobacco Free Program

Baby & Me is an evidence-based smoking cessation program created to reduce the burden of tobacco on the pregnant and postpartum population. There are several Upstate chapters that offer help year-round.

SC Association of Nonprofit Organizations

The mission of the S.C. Association of Nonprofit Organizations (SCANPO) is to serve, support and strengthen nonprofit organizations for a better South Carolina. SCANPO’s website features a search of all member nonprofit agencies, including social service organizations.

Goodwill Industries of Upper SC, Inc.

Goodwill Industries of Upper SC, Inc. helps people with disabilities and special needs become fully independent citizens through training and employment leading to job placement. It provides rehabilitation service, training, work adjustment, employment opportunity, and placement in competitive industry for people with disabilities and special needs.

Christmas in Action

Christmas in Action is a one-day home improvement project in which volunteer teams repair the homes of residents who are unable to do the needed repairs

Mental Health Association of the Piedmont, Inc.

This organization works to promote mental health and prevent mental illnesses through advocacy, education, research and service.

AccessHealth Spartanburg

AccessHealth Spartanburg connects clients who are low-income, residents of Spartanburg county, and who are un-insured or under-insured get connected to free/affordable healthcare. This non-profit is set up to connect people with doctors who have donated their time and services in order to receive medical assistance. We are located at 631 N Church St. Spartanburg, SC 29301

TOTAL Ministries

TOTAL Ministries focuses on emergency financial assistance. TOTAL provides rental assistance, mortgage assistance, heating assistance, prescription payments, clothing, food, and, on limited occasions, transportation assistance. All services are free to requestors.

Piedmont Care

Piedmont Care is a nonprofit organization serving the Spartanburg, Cherokee, and Union communities by providing HIV/AIDS care, prevention, and advocacy.

Mobile Meals Service of Spartanburg

Mobile Meals is a home-delivered hot meal service for the homebound of Spartanburg County who are unable to prepare their own food. No charge is made for the meals, delivered Monday through Friday, and there are no income or age restrictions for potential recipients. Volunteers are the “life line” of Mobile Meals; it takes at least 150 volunteers per day to see that meals are delivered to the 2,000 recipients served each weekday.

Fuller Center for Housing of Spartanburg

The mission of FCH Spartanburg is to reach out and bless residents of the community in need of home repairs. While many groups find repairs to be prohibitive because of their cost and complexity, FCH Spartanburg realizes how life-changing repairs and renovations can be. They have accepted the challenge of improving the lives of their neighbors through this ministry. The Fuller Center for Housing of Spartanburg has completed numerous Greater Blessing Box projects during this past year with two additional major renovations. The work has impacted the lives of over 22 individuals, with more than half of those being handicapped, by providing decent living conditions.

First Steps

South Carolina First Steps to school Readiness (‘First Steps’) is a comprehensive, results-oriented statewide education initiative to help prepare our children to reach first grade healthy and ready to succeed.

  • Cherokee County First Steps, call 864-487-9466.
  • Laurens County First Steps, call 864-984-3568.
  • Spartanburg County First Steps, call 864-327-4900.
  • Union County First Steps, call 864-429-1730, ext 32.
Battered Woman/Domestic Violence Hotline

Help is only a phone call away….


Affirm is located in Greenville, SC, and serves the entire nine-county area known as the Upstate and provides a safe place where GLBTQ youth meet and form friendships, build positive self esteem, and develop skills necessary for dealing with a negative environment.